Introduction and purpose: Groundwaters provide the main source of drinking water in Mazandaran province; however, the high concentration of soluble salts and hardness in these waters result in probable sedimentation and corrosion in water distribution systems of these areas. Therefore, the aim of this study was to determine the sedimentation and corrosion potential in the drinking water resources in Amol, Babol, Ghaemshahr, Sari, and Neka in the second and first halves of 2015 and 2016, respectively. Methods: A total of 192 water samples from selected cities of Mazandaran province were tested using determining parameters of sedimentation and corrosion indices by a standard method. The indices, such as Langelier saturation, Ryznar stability, Puckorius scaling, Aggressive, and Larson-Skold were determined using relevant data. Results: The results of the study showed that out of 192 analyzed samples in the surveyed cities, 76 and 81.3 % of them had the sedimentation propertiesand potentials considering Ryznar stability and Langelier saturation indices, respectively. With regard to Puckorius scaling index, sedimentation potential was observed in 68.8 % of water samples. Aggressive and Larson-Skold indices have also showed sedimentation properties of water. Conclusion: It can be concluded that the drinking water in the water distribution systems of these cities has relatively sedimentation properties.