TY - JOUR T1 - The effects of 8 weeks of aerobic training on serum levels of chemerin and omentin in overweight women TT - بررسی تأثیر هشت هفته تمرین هوازی بر سطوح سرمی کمرین و امنتین در زنان دارای اضافه وزن JF - J-Health-Res-Commun JO - J-Health-Res-Commun VL - 4 IS - 4 UR - http://jhc.mazums.ac.ir/article-1-320-en.html Y1 - 2019 SP - 32 EP - 40 KW - Chemerin KW - Exercise KW - Omentin KW - Overweight N2 - Introduction and purpose: Obesity is one of the most important causes of mortality in developing countries. Omentin-1 and chemerin, as cytokines secreted by adipose tissue, are associated with obesity. Chemerin is considered a bridge between obesity and the exacerbation of diabetes type II. On the other hand, omentin-1 plays a role in regulating energy metabolism and body fat distribution in the body. The aim of the present study was to determine the effect of 8-week aerobic training on the serum levels of chemerin and omentin-1 in overweight women. Methods: This semi-experimental study was conducted on 21 overweight women with a pretest-posttest design and a control group. The study population was randomly divided into two groups of exercise (n=11) and control (n=10). The training program consisted of moderate aerobic training, including 30 min of running within 50-70% of maximum heart rate that was controlled with a Polar watch. This intervention was performed 3 sessions a week for 8 weeks. Blood samples were collected 48 h before the first session and 48 h after the last training session to measure the levels of serum omentin-1, chemerin, lipid profile, and insulin. Analysis of covariance was used to assess the differences between the groups. Results: The serum chemerin levels showed a significant reduction in the exercise group as compared to that in the control group (P=0.023). In addition, the serum levels of omentin-1 significantly increased in the exercise group, compared to that in the control group (P≤0.001). Conclusion: Aerobic exercises can improve the body composition and regulate the serum levels of insulin and glucose, thereby regulating the serum levels of chemerin and omentin-1 as adipokines. It seems that 8 weeks of aerobic exercise training accompanied by the elevation of omentin-1 level and reduction of chemerin level and factors related to obesity have an important role in the improvement of cardiovascular health and metabolic disorders associated with obesity in overweight women. M3 ER -